Feed And Grain - Macrolides

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Feed & Grain

Charm II Macrolide Test for Feed and Grain
>> Available in kits of 100 and 500 tests

charm ii_newlogo Charm II is the only rapid testing system to detect all members of the macrolide antibiotic family in feed and grain. Macrolide antibiotics function though the inhibition of protein synthesis in bacterial cells. The macrolide family of antibiotics includes erythromycin, pirlimycin, spiramycin, tilmicosin, tulathromycin, and tylosin. Macrolides are closely related structurally to the lincosamide family of antibiotics including lincomycin and clindamycin, and often cross-react on macrolide tests.

CHARM II MACROLIDE TEST AT A GLANCE
     • Detects macrolides and lincosamides
     • 10 minute assay time
     • 10 to 15 minute preparation time
     • 6 to 12 samples in assay
     • Same system can test multiple commodities for multiple residues

Charm II Macrolide Test for Feed and Grain Detection Levels

Drug	Test Sensitivity (ppb)
Erythromycin	1000
Lincomycin	2500
Pirlimycin	2000
Spiramycin	1000
Tilmicosin	1000
Tylosin	1000

How It Works
Charm II Macrolide Tests use a binding reagent with specific receptor sites that bind macrolide and lincosamide drugs. The binder is added to a sample along with labeled erythromycin (tracer). Any macrolide/lincosamide drugs in the sample compete for the binding sites with this tracer. The amount of tracer that binds to the receptor sites is measured and compared to a previously determined Control Point. The Control Point is the cutoff point between a negative or positive sample. The greater the amount of tracer measured, the lower the macrolide/lincosamide concentration in the sample. The smaller the amount of tracer measured, the greater the macrolide/lincosamide concentration in the sample.