|
The macrolide family of antibiotics includes the well-known drugs: erythromycin, pirlimycin, and lincomycin, along with the lesser-known drugs: tylosin, spiramycin, and tilmicosin.
| Recommended Screening / Detection Levels |
|
Macrolides:
|
Tissue1
ppb
|
Egg1
ppb
|
Urine2
ppb
|
Serum3
ppb
|
Feed4
ppb
|
Grain5
ppb
|
Honey5
ppb
|
Milk
ppb
|
|
Erythromycin
|
100
|
200
|
500
|
500
|
1000
|
1000
|
10
|
40
|
|
Tylosin
|
400
|
500
|
2000
|
2000
|
1000
|
1000
|
15-20
|
50
|
|
Spiramycin
|
400
|
500
|
2000
|
2000
|
1000
|
1000
|
20
|
50
|
|
Pirlimycin
|
600
|
800
|
3000
|
3000
|
2000
|
2000
|
40
|
80
|
|
Tilmicosin
|
50
|
200
|
500
|
500
|
1000
|
1000
|
40
|
40
|
|
Lincomycin
|
400
|
500
|
2000
|
2000
|
2500
|
2500
|
30
|
100
|
|
Tulathromycin
|
100
|
200
|
500
|
500
|
500
|
500
|
20
|
20
|
NOTES:
- Preparation dilution 1 part sample to 3 parts buffer. Alternative control point procedure may be used to enhance sensitivity 2 fold.
- Dilution range 1 part sample to 100-150 parts buffer to predict tissue action levels. Minimal allowable dilution 1:4 will enhance sensitivity 25 fold.
- Dilution 1 part sample to 20 parts buffer to predict tissue action levels. Minimal allowable dilution 1:4 will enhance sensitivity 5 fold.
- Dilution 1 part sample into 2 parts extract, 1 part extract to 25 parts buffer.
- Dilution 1 part to 4 parts for beta-lactams, macrolides, streptomycins; 1 part to 10 parts for Sulfa Drugs and Tetracyclines; and 1part to 20 parts for Amphenicols.
|
Antibiotic Tests 
